Crispr Cas9 Genome Editing System In Human Stem Cells Current Status

CRISPR Cas9

CRISPR Cas9 Sun J et al Brief Funct Genomics 2020 CRISPR Cas9 Cas9 tracrRNA crRNA

CRISPR Cas9 , CRISPR Cas CRISPR Cas CRISPR repeat spacer Cas

CRISPR

CRISPR DNA Clustered Regularly Interspaced Short Palindromic Repeats

RNA CRISPR Cas13 , CRISPR Cas13 RNA CRISPR CRISPR

, CRISPR CRISPR Cas DNA DSB Cas9

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CRISPR Cas9

CRISPR Cas9 CRISPR Cas9 Cas9 RNA single guide RNA sgRNA Cas9 RuvC HNH RuvC HNH

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CRISPR Cas 2 CRISPR Cas CRISPR Cas CRISPR Cas . CRISPR Cas9 ZFN TALEN DNA ZFN TALEN CRISPR CRISPRa CRISPR activation dCas9 dCas9

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