IJMS Free Full Text DNA Deamination Is Required For Human
Although the APOBEC3 family of single stranded DNA cytosine deaminases is well known for its antiviral factors these enzymes are rapidly gaining attention as prominent sources of mutation
IJMS Free Full Text DNA Deamination Is Required For Human , May 26 2023 nbsp 0183 32 Naumann JA Argyris PP Carpenter MA Gupta HB Chen Y Temiz NA Zhou Y Durfee C Proehl J Koniar BL et al DNA Deamination Is Required for Human APOBEC3A
DNA Deamination Is Required For Human APOBEC3A Driven
May 26 2023 nbsp 0183 32 First we show that APOBEC3A alone is capable of driving tumor development without Tp53 knockdown as utilized in prior studies Second we show that the catalytic
PDF DNA Deamination Is Required For Human APOBEC3A Driven , Apr 28 2023 nbsp 0183 32 A3A induced tumorigenesis occurs through a DNA deamination mechanism A Structure of A3A bound to single stranded DNA orange and yellow Key A3A residues are
PDF DNA Deamination Is Required For Human APOBEC3A Driven
PDF DNA Deamination Is Required For Human APOBEC3A Driven , This work shows that APOBEC3A alone is capable of driving tumor development without Tp53 knockdown as utilized in prior studies and shows that the catalytic glutamic acid residue of
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DNA Deamination Is Required For Human APOBEC3A Driven
DNA Deamination Is Required For Human APOBEC3A Driven May 2 2023 nbsp 0183 32 Here we investigate the molecular mechanism of APOBEC3A driven tumor development using the murine Fah liver complementation and regeneration system First we
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May 26 2023 nbsp 0183 32 Europe PMC is an archive of life sciences journal literature Search life sciences literature 42 493 996 articles preprints and more DNA Deamination Is Required For Human APOBEC3A Driven . Although the APOBEC3 family of single stranded DNA cytosine deaminases is well known for its antiviral factors these enzymes are rapidly gaining attention May 26 2023 nbsp 0183 32 One explanation for this association is that p53 inactivation may be required for cells to tolerate APOBEC3 catalyzed DNA uracilation and the ensuing DNA damage
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